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10.1021/acs.jafc.2c05262 14 ChengK.HuangY.WangC

TBWA Worldwide global director Lee Clow, CEO Tom Carroll, chairman Jean-Marie Dru, and TBWA Media Arts Lab president James Vincent

doi: 10.1111/jcpp.13186

Pharmacological Approaches Anti-spasmodics, including dicyclomine, hyoscyamine, and hyoscine, may reduce abdominal pain by relaxing intestinal smooth muscle, but can worsen constipation and lack strong evidence for IBS-C pain relief [104, 105]