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First, rats were used in a portion of the study, which can only offer restricted data

Treatment continued until the occurrence of radiologic progression, as defined by mRECIST, 44 symptomatic progression, unacceptable toxicity, or death

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Conclusions and Future Perspectives Thiamine deficiency, regardless of the underlying mechanism (genetic or epigenetic), impairs critical TPP-dependent enzymes involved in intermediary metabolism and antioxidant defenses

Unni V, Abishad P, Prasastha Ram V, Niveditha P, Yasur J, John L, Prejit N, Juliet S, Latha C, Vergis J, Kurkure NV (2022) Green synthesis, and characterization of zinc oxide nanoparticles using Piper longum catkin extract and its in vitro antimicrobial activity against multi-drug-resistant non-typhoidal Salmonella spp