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Huang T, Wang J, et al

By addressing the root causes of pain through physical mechanisms, these therapies reduce the necessity for anti-inflammatory and pain-relieving drugs, which often come with side effects

PLD A class of phospholipases that hydrolyze the phosphodiester bond of phosphatidylcholine is phospholipase D, whose action leads to the formation of a signaling molecule, phosphatidic acid, which participates in many fundamental cellular processes such as vesicular transport, exocytosis, autophagy, and consequently regulates cellular metabolism, including contributing to tumorigenesis [52]

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