In a multi-institutional retrospective study of 3,047 cancer patients, weight loss occurring prior to the initiation of systemic chemotherapy, independent of disease stage and patient performance status, was predictive of disease progression and poor prognosis.[2] Cancer cachexia is characterized by an inflammatory state, insulin resistance, and loss of skeletal muscle due to protein breakdown and lipolysis
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Symptoms of Chronic Diarrhea Loose or watery stools lasting more than 4 weeks Urgency to use the bathroom Abdominal cramping or bloating Fatigue and dehydration Weight loss or poor appetite Possible blood or mucus in stool Causes of Chronic Diarrhea Chronic diarrhea may be due to many conditions, including: Irritable bowel syndrome (IBS) Inflammatory bowel disease (IBD) Crohns disease, ulcerative colitis Infections (bacterial, parasitic, viral) Medication side effects (antibiotics, metformin, heartburn medicines) Food intolerances lactose, gluten, artificial sweeteners Endocrine disorders diabetes, thyroid disease Cancer or polyps (less common, but important to rule out) Pathophysiology (Whats Happening Inside) by Internist Geriatrician PCP Physician Georgetown TX Chronic diarrhea can occur when the intestines: Fail to absorb enough water and nutrients Produce excess fluid due to inflammation or infection Are stimulated by certain hormones or medications Move food too quickly through the digestive tract Your internal medicine doctor near me can help identify which mechanism is affecting you
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