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Hypoxia pretreatment promotes chondrocyte differentiation of human adipose-derived stem cells via vascular endothelial growth factor

More directly, supplementation with propionatea representative postbiotic of SCFAssignificantly increased the bone formation marker osteocalcin and decreased the bone resorption marker -crosslaps ( CTx) in patients with multiple sclerosis, highlighting the potential of microbial metabolites to directly regulate bone homeostasis (253)

Cell Lines and Culture Conditions Colorectal adenocarcinoma cell line HT29 (ATCC, HTB-38) and human skin fibroblast cell line Hs27 (ATCC, CRL1634) were obtained from ATCC (Manassas, VA, United States)