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Andersen, E

Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: implications in dopamine cytotoxicity and pathogenesis of Parkinsons disease

When damaged mitochondria exceed the capacity of mitophagy and fusion mechanisms, cells ultimately succumb to apoptosis or necrosis under the dual assault of energy failure and persistent inflammation

Non radicals Hydrogen peroxide (H 2 O 2 ) H 2 O 2 is an important ROS molecule primarily produced intracellularly through enzymatic reactions, notably by NOX family enzymes which are key dedicated generators of ROS [71]

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