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Description

Dreyer A

& Rangnekar, A

Sirtuins 1 and 2 Are Universal Histone Deacetylases

It plays a role in neutralizing oxidative stress and may even contribute to cardiovascular health in moderate amounts

Discussion We have identified compounds ( 1 - 10 ) that act as non-covalent inhibitors of TGR with druglike properties as demonstrated by efficacy in mice infected with S