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Stress conditions promoting instability and denaturation of proteins induce the release of HSF-1, which the activity is associated with the expression of HSP70 in the myocardium, skeletal muscle, and human leucocytes [76, 107]

The samples for hepatic metabolomics analysis were part of a larger metabolomics study of the plasma, kidney, heart, and lungdata from which have been reported 6,15

This is because collagen helps to maintain the skins structural integrity

The device operates based on the suction method, where negative pressure is applied to the skin, and the resulting deformation is measured to evaluate the biomechanical properties of the skin