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Two possibilities explain the animal oral data: Local action without systemic absorption: BPC-157 at high luminal concentrations acts directly on GI epithelium, submucosal vessels, and enteric neurons without requiring absorption into the bloodstream

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Iron overload plays a critical factor in ferroptosis

Ecm38p, -Glutamyl transpeptidase, which is involved in - Glu-met degradation is a vacuolar enzyme