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It also consistently elevates IL-10, enhancing anti-inflammatory capacity in obese men, type 2 diabetes patients, and post-percutaneous coronary intervention (PCI) patients (135, 141, 142)

Further studies are warranted to evaluate the safety and effectiveness of coffee enemas, as well as to analyze how coffee enemas affect bile excretion

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Zhenlie Huang, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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