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Current research posits that chronic inflammation may be triggered by irritants resulting from the local degradation of sebum by Malassezia [95]

A few authors have proposed that folate may actually worsen the neurologic dysfunction

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In this study, SGLT2 inhibition-associated renal protection was mediated by the elevation of ketone bodies, which suppressed the mechanistic target of rapamycin complex1 (mTORC1) signaling (as assessed by phosphorylation of the S6 protein) hyperactivation, thereby alleviating DKD (69)