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-synuclein fibrillation is strongly affected by metal ions like zinc, copper, iron and calcium (Uversky et al., 2001)

Neurosci Bull 38(10):12671270 Ding XS, Gao L, Han Z, Eleuteri S, Shi W, Shen Y, Song ZY, Su M, Yang Q, Qu Y, Simon DK, Wang XL, Wang B (2023) Ferroptosis in Parkinsons disease: molecular mechanisms and therapeutic potential

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Vitamin E suppression of microglial activation is neuroprotective

Proton magnetic resonance spectroscopy (MRS) enables the detection of glutamate in the living human brain and meta-analyses of previous MRS studies in depressed patients have suggested that glutamate levels are decreased in anterior brain regions