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IgG26AW has high affinity, high neutralization ability and occupies a new binding epitope that binds both to IL-1RI and IL-1RAcP, which has been validated in tumors and may be a potential drug for RA in the future (Kuo et al., 2021)

Zhu et al., 2020), the significantly enriched mucinophilic genus Akkermansia , a representative of the Verrucomicrobia phylum, was negatively associated with cardiovascular disease and inflammatory response