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Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E et al (2003)

"Pilot Study of the Effect of Methyl B12 Treatment on Behavioral and Biomarker Measures in Children with Autism." The Journal of Alternative and Complementary Medicine 16.5 (2010): 555-60

They should be sourced from licensed compounding pharmacies, not unregulated online vendors, and used with appropriate lab monitoring

From what has been mentioned so far, it is very likely that the carcinogenic effect of IDH1 R132 and IDH172 is mediated through the elevated cellular (D)-2HG levels originating from cytoplasm by IDH1 R132 or from mitochondria by IDH2 R172 (where it exits the mitochondria and enters the cytoplasm)