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The metabolite analysis demonstrated that Nrf2 strongly promotes purine nucleotide synthesis, resulting in the increased production of purine nucleotides

Nguyen et al., 2018

Formulations and compositions thus may be designed in accordance with the invention for delivery by any suitable route of administration

According to the results of a meta-analysis based on fifteen studies enrolling a total of 1633 tumor patients, positive expression of CD44v9 was associated with poor overall survival and relapse-free survival, compared with cancer patients with negative expression of CD44v9 [127]

Acetate, propionate, and butyrate are essential microbial metabolites that in addition to host-centric functions in energy metabolism and immunological control, affect bacterial communities by modifying luminal pH, suppressing pathogenic overgrowth, and regulating quorum-sensing pathways 43