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Therefore, emphasis should be placed on combining energy-restriction with a high protein diet and physical activity, to provide the maximal anabolic stimulus, ensuring weight loss is not associated with loss of muscle mass, or, more importantly, muscle strength [67, 68]

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Severe reactions to vaccines are also caused by allergic reactions, such as anaphylaxis, a reaction which can manifest as hives symptoms, difficulty breathing, throat, tongue, or lips swelling, severe itching, dizziness and skin rash

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The North America ALS/IGF-I Study Group