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Finally, -diversity distance matrixes were analyzed using PERMANOVA in QIIME2, whilst the visualization of both - and -diversity was performed via integrating the packages QIIME2R [43] and ggplot2 [44]

For example, RN104 (2- [2-(cyclohexyl methylene) hydrazinyl]-4-phenylthiazole) is a thiazole hydrazone derivative with significant antifungal activity

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