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Figure 3 4.1.1 Role of iron metabolism in ischemic stroke Prior to the formal identification of ferroptosis, studies had already linked iron accumulation to neuronal damage in both clinical settings and animal models of cerebral ischemia (131)

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Briefly, recombinant GSTO1 was diluted into 50 mM Tris-HCl (pH 8.0) buffer containing the fluorophore 1,8 ANS (0.3 mM) to a final concentration of 0.3 mg ml 1

Insights from non-traditional model organisms

The most common drugs currently used to treat lung diseases are still chemical drugs, but this may lead to drug resistance and damage to healthy organs in the body