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Treatment with ACEIs or ARBs reduces EGR1 expression in glomeruli, inhibits renin expression, decreases secretion of TNF-a and fibronectin proteins (FN) from tethered cells, slows tethered cell injury, and affects the behavior of MCs [75]

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Discontinuation There is no documented discontinuation syndrome and no need to taper off

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Ye Y., Wang C., Zhang X., Hu Q., Zhang Y., Liu Q., Wen D., Milligan J., Bellotti A., Huang L., Dotti G., Gu Z