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MLC phosphorylation (pMLC) by either myosin light chain kinase (MLCK) or -associated coiled coil containing protein kinase (ROCK) stimulates tight junction regulation via contraction of the perijunctional actomyosin ring (PAMR) (45, 46)

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153(1):469480 Rowlinson SW, Yoshizato H, Barclay JL, Brooks AJ, Behncken SN, Kerr LM et al (2008) An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway