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You go hard or you go home. Though the series is new, the concept is a proven commodity: Originally thought up on a whim by Krasinski, his wife Emily Blunt and British Office co-creator Stephen Merchant while road-tripping, the lip-sync game quickly found a home on their friend Jimmy Fallons talk shows, starting in 2013

Gene expression was subsequently quantified by performing quantitative real-time PCR (qRT-PCR) by using the cDNA as template

The names of the repository/repositories and accession number(s) can be found below: GEO accession GSE210703

Many of the pathophysiology and the signaling pathways involved in this process are also shared by the development of MDS-related TOD

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