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Increased bleeding risk in adults who weigh less than 110 pounds (50 kg) undergoing certain surgeries

In brief, tissue homogenates were diluted 1:20 in cold buffer to obtain a concentration of 5mg tissue/ml

General Mol

Among these mediators, TGF-1 is particularly significant, as it directly activates HSCs and stimulates the synthesis of extracellular matrix proteins, thereby promoting fibrogenesis