l carnitine can cause kidney or liver damage Medium-chain fatty acid oxidation is independent of l-carnitine in and but not in heart and skeletal muscle Carnitine: Genetic Variants Affecting Mitochondrial

The endolysosomal system is essential for maintaining cellular proteostasis and its dysfunction is thought to be involved in accumulation of pathological proteins in various neurodegenerative diseases

Choi JW, Ohn JH, Jung HS, Park YJ, Jang HC, Chung SS, Park KS (2018) Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction

1b, c), suggesting that WH2_1 might constitute the G-actin binding domain

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However, combination therapy is not appropriate for everyone and requires medical evaluation and supervision