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DNA and nucleosome-binding assay Unless indicated otherwise, all steps were performed on ice or at 4C

However, because most somatic cells lack telomerase, the length of their telomeres shortens over time, leading to senescence once the telomeres reach a threshold length

Slc25a44 flox/flox , herein SLC25A45 KO mice) ( Fig

Free Radical Biol.Med

However, at 144 hpf, thyroid tissue appeared enlarged in around 55% (170/312) of the nrf2a crispants compared with their adamtsl2 crispants and noninjected siblings (Fig S1IL)