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Other key peroxide scavengers are peroxiredoxins (Prx

One study noted that Semaxs effects on neural tissue were observable within minutes of administration in animal models, suggesting a rapid onset of activity at the cellular level a detail researchers cite as evidence that Semax acts through direct CNS signaling rather than a slower, systemic hormonal route

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2.6 Therapeutic perspectives Ferroptosis integrates multiple metabolic pathways: (1) iron catalysis driving hydroxyl radical formation, (2) lipid metabolism determining peroxidation substrates, (3) thiol metabolism maintaining the redox environment, and (4) selenium metabolism enabling selenoprotein-based detoxification

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