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In vitro and ex vivo uptake of GSH across the intestinal epithelium, and fate of oral GSH after in vivo supplementation

& Willenbring, H

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Role of ferroptosis in mitochondrial damage in diabetic retinopathy

However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)