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Microglial cells are capable of differentiating into distinct functional states, including the M1 phenotype, which exerts pro-inflammatory and neurotoxic effects, and the M2 phenotype, which is linked to anti-inflammatory and neuroprotective actions 58

Collectively, the results of this study illustrate that AOD9604 exerts distinct metabolic effects depending on the genetic background of the animal and the presence of functional 3-ARs

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N., Mayer, J