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The central role of glutathione in the pathophysiology of human disease, 2007 GSH Mitochondrial Transport glutathione and mitochondrial GSH can be transported to mitochondrial matrix by different carriers, particularly the 2-oxoglutarate carrier (OGC) and the dicarboxylate carrier (DIC), located in the mitochondrial inner membrane

Vice versa, malfunction in oxidative protein folding is assumed to affect the redox potential of the lumenal glutathione pool

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Remarkably, at this higher dose (240 g three times a day), the mean reduction in body weight with pramlintide treatment over 16 weeks was approximately twice that previously observed over a similar time-frame in insulin-treated subjects with type 2 diabetes who were treated with lower pramlintide doses (120 g)

Rees DD, Palmer RM, Moncada S: Role of endothelium-derived nitric oxide in the regulation of blood pressure