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In obesity and insulin resistance, mitophagy markers, including LC3BII, Parkin, FUNDC1, and BNIP3, are generally reduced in both human and animal studies, reflecting compromised mitochondrial turnover

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First, two extensive, population-based prospective cohortsthe CHARLS cohort in China and the UK Biobank cohort in the United Kingdomwere analysed, allowing evaluation of the link between E-sdLDL-C levels and incident CVD across diverse ethnicities and health care systems

As previously described by Carabao et al