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Establishment of protocols for global metabolomics by LC-MS for biomarker discovery

L., Ingram, K

Most of our patients benefit from combining two or three of these mechanisms in a structured plan rather than chasing one modality alone

doi: 10.1016/j.bbrc.2007.03.141 138 NagaokaI.SuzukiK.NiyonsabaF.TamuraH.HirataM

Indeed, in 23 patients out of a total of 25, 5-MTHF in CSF was low despite normal serum folate treatment with folinic acid for a year restored folate levels and led to clinical improvements