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For the final stage of maturation into functional hepatocyte-like cells (HLCs), the proliferative HBs were cultured in hepatoZYME-SFM medium supplemented with 1X GlutaMAX

When all participants were analyzed regardless of treatment adherence, weight reduction trends were consistent with those from the primary analysis, confirming robustness of the findings

1 2 Journal of Applied Physiology

Activating the HGF/c-Met signaling pathway initiates a cascade of events that: Stimulates synaptogenesis the physical formation of new synaptic connections between neurons Promotes dendritic spine formation the small protrusions on neurons essential for receiving signals Enhances synaptic density in brain regions associated with learning and memory Supports neural stem cell activity and neuroplasticity Reduces neuroinflammatory signaling, offering a neuroprotective effect Structural vs

the HGFc-Met and BDNF synaptogenesis case