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Napolitano et al., 2022) (Figure 1)

Likewise, PA restored cadmium-induced Nrf2 inhibition to prevent autophagy inhibition and NLRP3 inflammasome activation, providing novel insights into the protection of PA against cadmium-induced hepatic cell damage (Yu et al., 2021)

Their Phase 2 clinical trial found that xanthohumol, a natural compound from hops, moved patients with active Crohn's disease into remission within 4 weeks, with no adverse effects

Hypoxia, a key pathogenic mechanism underlying PH, serves as a fundamental driver of its onset and progression [68, 69]