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Furthermore, other post-translation modifications of keap-1 (glycosylation, phosphorylation, glutathionylation and SUMOylation) is also reported indicating that the type of modifier is critical to determine how Keap-1 is chemically modified and Nrf2 is released (Song et al., 2023)

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If you feel sluggish and tired often simply increasing your water intake can help you feel immediately more alert and energised