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Transient CSF1R inhibition ameliorates behavioral deficits in Cntnap2 knockout and valproic acid-exposed mouse models of autism

These cellular changes contribute to symptoms such as persistent pelvic pain, urinary urgency and frequent urination (Lin et al., 2021)

In this study, the authors show that it is not the mitochondrial ATP production, but the uninterrupted flux through the TCA cycle, enabled by the low NADH/NAD + ratio, is the major limiting factor for cell proliferation

Sections (50 m thick) were cut using a cryostat and individually collected in 96-well culture plates filled with 0.1 M phosphate buffer (PB)

Abstract The recreational abuse of addictive drugs poses considerable challenges to public health, leading to widespread neurotoxicity and neurological dysfunction