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It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

Upon measuring grip strength, the researchers found that treatment on its own in sedentary mice increased grip strength by about 25%, compared to exercise alone increasing grip strength by about the same percentage

Diabetes 68:527542

Tests in bacteria, cells, and mice all came back negative, suggesting the compound does not pose carcinogenic risk through DNA damage mechanisms