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However, a longer (nine months) duration of Grk2 knockdown was reported to lead to a nitric oxide-dependent vasodilation which overcomes vasoconstriction, making Grk2 +/ mice resistant to the development of hypertension [31]

Hayeshi R, Chinyanga F, Chengedza S, Mukanganyama S: Inhibition of human glutathione transferases by multidrug resistance chemomodulators in vitro

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