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In the event that the funds purchase Underlying ETF shares after the first day of a Target Outcome Period and the Underlying ETF has risen in value to a level near to the cap, there may be little or no ability for the funds to experience an investment gain on its shares, however, the funds will remain vulnerable to downside risks

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Benefits & Side Effects (Research Context) Observed / Investigated Effects Increased weight gain and nitrogen retention in certain animal models under specific conditions Growth support in models with reduced renal mass (dosedependent protocols studied) Safety Signals / Constraints Biodistribution work suggests rapid internalization/catabolism after receptor binding and fast clearance characteristics in certain setups

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