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Metformin users : Chronic metformin therapy can lower B12 levels by up to 30%

Additionally, by blocking Toll-like receptor 4, naltrexone may also alleviate neuroinflammation in ME/CFS [149]

Peer review Peer review information Nature Reviews Urology thanks Ralf Henkel, Sandro Esteves and Luca Boeri for their contribution to the peer review of this work