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Additionally, glutathione's role as a substrate for glutathione S-transferase (GST) enzymes can sequester bile acids, further reducing bowel stimulation

[DOI] [PubMed] [Google Scholar] 29.Johnson M.P., Hoffman A.J., Nichols D.E

Lipid peroxidation The mammalian ALOX family, consisting of six members (ALOXE3, ALOX5, ALOX12, ALOX12B, ALOX15 and ALOX15B), plays a tissue- or cell-dependent role in mediating PUFA peroxidation to produce AA/AdA-PE-OOHs, thus causing ferroptosis

According to research on real-world sequential therapies, even after numerous treatment attempts, almost 30% of MDD patients do not experience remission