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ARTCHR combination reshapes spatial and drug resistancephenotypic disparities in Mrps and Bcrp mRNA expression under P-gp deficiency To streamline data analysis, we focused on drug-resistance-related differences that can be fully reversed by ART montherapy and combination treatment, or by Mdr1a deficiency

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The therapeutic potential of PRP is primarily mediated by its high concentration of growth factors, such as TGF-1, IGF, and VEGF, which regulate angiogenesis, cellular proliferation, anti-apoptotic signaling, and tissue remodeling