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( B ) The levels of serum total T 4 and TSH in WT C57BL6/j (also referred to as TG +/+ ), Tg-KO ( TG / ), and Tg +/ heterozygous mice ( n = 525 per group, 3.3 1.3 mo

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Tumour-derived human growth hormone as a therapeutic target in oncology

Glutaminolysis inhibitors Inhibitors of glutamine metabolism, particularly the glutaminase inhibitor CB-839 (telaglenastat), have shown efficacy in preclinical models of NSCLC as illustrated in Table 2