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Some preferentially take in T4 from the serum and convert it to T3 (e.g., brain, pituitary, heart, brown adipose tissue), whereas others are more reliant on serum T3 (e.g., liver, kidneys, adrenal glands) (10)

Discussion Cancer as a metabolic disease is gaining attention with the growing interest in precision medicine (90).While cancer is highly regarded as an outcome of genetic mutations happening within the patient, emerging evidence suggests the role of metabolic dysfunction as a predecessor of genetic abberrations ( In the context of cancer prevention, early screening and detection continue to serve as foundational strategies for reducing incidence and improving outcomes

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[DOI] [PubMed] [Google Scholar] 66

Obesity is not a one-size-fits-all issue