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One is indeed Gsi and our data strongly suggests that its preferred substrate is oxidized and not reduced glutathione

Niveles de superxido dismutasa y catalasa en enfermedades del anciano [Superoxide dismutase and catalase levels in diseases of the aged]

Using anaerobic transient state spectrophotometric methods, redox changes for the FAD and NADPH were observed and the function of specific residues was defined from observation of charge transfer absorption transitions that are indicative of specific complexations and redox states

Further, these data suggest that at acute time points following Gclc genetic deletion, compensation by NRF1 could be responsible for the dispensable role of NRF2 in GSH-depleted conditions