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Measurement of intracellular calcium Ca 2+ signal analysis The intracellular free calcium concentration level [Ca 2+ ] i was analysed with a Fura-2 a.m

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CDCl 3 ) 63.0 (CH 2 , C-1), 52.3 (CH, C-5), 47.1 (CH 2 , C-6), 32.6 (CH 2 , C-4), 32.3 (CH 2 , C-2), 26.0 (3CH 3 , SiC(CH 3 ) 3 ), 22.3 (CH 2 , C-3), 18.4 (C, SiC(CH 3 ) 3 ), 5.3 (2CH 3 , Si(CH 3 ) 2 )

OCT4 and NANOG expression marks ICM cells destined to form the fetus, while CDX2 and GATA3 expression characterizes TE cells that will form extraembryonic structures [383, 398, 399]

An array of preclinical and clinical studies have demonstrated that CBD possesses a variety of beneficial properties, including antioxidant, immunomodulatory, anti-inflammatory, neuroprotective, antipsychotic, procognitive, anti-anxiety, and anti-proliferative effects (Castillo et al