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Tretinoin (prescription retinoid): 4 of 10 (40%)

Vitamin B-5 16

doi: 10.1136/jitc-2022-005020 Summary Keywords aging, type 2 inflammatory, chronic pigmentary disorders, skin cancer, skin Citation Zhang M, Lin Y, Han Z, Huang X, Zhou S, Wang S, Zhou Y, Han X and Chen H (2024) Exploring mechanisms of skin aging: insights for clinical treatment

Degeneration of myelin sheaths occurs with aging 5 , with particular vulnerability of newly discovered bridging myelin sheaths, by which OLs generate sheaths via an extension of the outer tongue of an existing sheath 93

Co-culture systems involving neurons, microglia, and astrocytes could elucidate the complex interactions within the neuroimmune network and provide deeper insights into the multifaceted roles of Irisin