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[8] On concentration: clinical studies generally use 1-3% in optimized delivery systems

Plaper et al., 2003)

MatsunoKYamadaHIwataKJinDKatsuyamaMMatsukiMet alNox1 is involved in angiotensin ii-mediated hypertension: a study in Nox1-deficient mice

Older adults who tend to have impaired digestion are one of the most susceptible populations

Serum holoTC is a better biomarker of recent B12 intake than serum B12 (or methymalonic acid or tHcy) because serum holoTC concentrations increase much faster after ingestion of B12 from a meal (i.e., 6 hours) or crystalline B12 from supplements