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Discovery of a novel missense variant in NLRP3 causing atypical CAPS with hearing loss as the primary presentation, responsive to anti-IL-1 therapy

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The primary subject of this article centers on the application of HWFDE technology

Results Co-treatment of Met or CQ, and low-dose AraC more effectively inhibited NALM-6 cell proliferation This study demonstrated that AraC, Met, and CQ significantly inhibited NALM-6 cell proliferation in a dose-dependent manner

Mitochondrial cardiolipin is required for supporting CD8 + T cell responses and memory [153], but how such function is related to the regulation of T cell survival was unclear