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In addition to serotonin, the gut microbiota can also modulate the balance of excitatory and inhibitory neurotransmitters

[33] Placebo-controlled trials have been deemed unethical in instances where not receiving treatment may lead to harm for the patient, such as an aggravation of symptoms or risk of death

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In the total population 26% (296) received Evusheld

and the last, researchers gave them a placebo with a trace amount of THC that wasn't enough to get them high