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Science 353:702704 Noguera JC, Kim S-Y, Velando A (2011) Pre-fledgling oxidative damage predicts recruitment in a long-lived bird

KPV reduces the inflammatory signaling from chronic hyperglycemia that drives ongoing nerve injury

Its deficiency leads to mitochondrial dysfunction, lactate and pyruvate accumulation, and consequently to focal thalamic degeneration, manifested as Wernickes encephalopathy or WernickeKorsakoff syndrome

PMID 12565892

The intense competition of glucose between liver cancer cells and CD8 + T cells results in the exhaustion of T cells due to the overexpressed key enzymes of liver cancer cells that control glycolysis, giving tumor cells an advantage in glucose uptake