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To overcome these research bottlenecks, future studies should conduct more systematic in vivo experiments to simulate the complex physiological microenvironment, while designing more rigorous experimental protocols to elucidate the precise mechanisms by which TCM target the Wnt/-catenin signaling pathway in CRC treatment

This indicates that NO and NaOCl may target similar specific thiols in mycobacteria that functions in the protection against ROS and RNS to ensure cellular survival and virulence under infection conditions

*Correspondence: Haider Raza, [email protected] This article was submitted to Metabolic Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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L-Glutathione supports the bodys natural antioxidant defenses by helping neutralize free radicals that form during normal metabolic activity